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Coenzyme Q 10 is a compound that is made naturally in the body. The body uses it to promote cell growth and to protect cells from damage that could lead to cancer. It also may help protect the body from side effects of some cancer treatments.
Animal studies have shown that coenzyme Q10 stimulates the immune system and increases resistance to certain infections and types of cancer.
There is only one reported randomized clinical trial with cancer patients. This trial reported that coenzyme Q10 decreases the effects of doxorubicin, a drug used to treat cancer, on the heart.
In 3 related studies with breast cancer patients, some beneficial results were found. Problems with the research, however, made it impossible to determine whether beneficial results were directly related to coenzyme Q10 .
Because coenzyme Q10 is marketed as a dietary supplement rather than a drug, it is not regulated by the U.S. Food and Drug Administration. For this reason, it has not been carefully evaluated for safety and effectiveness.
It is important that patients inform all of their health care providers about any therapies they are currently using or considering. This is to help ensure a safe and coordinated course of care. Coenzyme Q10 may affect the activity of other medicines.
What is coenzyme Q10?
Coenzyme Q 10 (also known as CoQ10, Q10, vitamin Q10, ubiquinone, or ubidecarenone) is a compound that is made naturally in the body. A coenzyme is a substance needed for the proper functioning of an enzyme, a protein that speeds up the rate at which chemical reactions take place in the body. The Q and the 10 in coenzyme Q10 refer to parts of the compoundís chemical structure.
Coenzyme Q10 is used by cells to produce energy needed for cell growth and maintenance. It is also used by the body as an antioxidant. An antioxidant is a substance that protects cells from chemicals called free radicals. Free radicals are highly reactive chemicals that can damage important parts of cells, including deoxyribonucleic acid (DNA). (DNA is a molecule inside cells that carries genetic information and passes it from one generation to the next.) This damage may play a role in the development of cancer.
Coenzyme Q10 is found in most body tissues. The highest amounts are found in the heart, liver, kidneys, and pancreas. The lowest amounts are found in the lungs. Tissue levels of coenzyme Q10 decrease as people get older.
What is the history of the discovery and use of coenzyme Q10 as a complementary or alternative treatment for cancer? Coenzyme Q10 was first identified in 1957. Its chemical structure was determined in 1958. Interest in coenzyme Q10 as a potential treatment for cancer began in 1961, when a deficiency of the enzyme was noted in the blood of cancer patients. Low blood levels of coenzyme Q10 have been found in patients with myeloma, lymphoma, and cancers of the breast, lung, prostate, pancreas, colon, kidney, and head and neck.
Studies have yielded information about how coenzyme Q10 works in the body to produce energy and act as an antioxidant. Some studies have suggested that coenzyme Q10 stimulates the immune system and increases resistance to disease. In part because of this, researchers have theorized that coenzyme Q10 may be useful as an adjuvant therapy for cancer. (Adjuvant therapy is treatment given following the primary treatment to enhance the effectiveness of the primary treatment.)
Have any preclinical (laboratory or animal) studies been conducted using coenzyme Q10?
Laboratory studies of coenzyme Q10 have focused on describing its chemical structure and how it works in the body. Animal studies have found that coenzyme Q10 stimulated the immune system and increased resistance to certain infections and types of cancer. Coenzyme Q10 helped to protect the hearts of animals given the anticancer drug doxorubicin, which can cause damage to the heart muscle.
Have any side effects or risks been reported from coenzyme Q10?
No serious side effects have been reported from the use of coenzyme Q10. Some patients using coenzyme Q10 have experienced mild insomnia (inability to sleep), elevated levels of liver enzymes, rashes, nausea, and upper abdominal pain. Other reported side effects have included dizziness, visual sensitivity to light, irritability, headache, heartburn, and fatigue.
Patients should talk with their health care provider about possible interactions between coenzyme Q10 and prescription drugs they may be taking. Certain drugs, such as those that are used to lower cholesterol or blood sugar levels, may reduce the effects of coenzyme Q10. Coenzyme Q10 may also alter the bodyís response to warfarin (a drug that prevents the blood from clotting) and insulin.
Coenzyme Q10 is used by the body as an antioxidant. Antioxidants protect cells from free radicals, which are highly reactive chemicals that can damage cells. Some conventional cancer therapies, such as anticancer drugs and radiation treatment, kill cancer cells in part by causing free radicals to form. Researchers are studying whether using coenzyme Q10 along with conventional therapies is positive (i.e., does not interfere with the effects of the conventional therapies or increases the therapiesí beneficial effects on cancer cells while protecting normal cells) or negative (i.e., interferes with the therapeutic effects).
CoEnzyme Q10 (Coq-10) Healthy Heart Formula:Recommended by doctors, Co Q10 plays a vital role in the treatment & prevention of heart disease, as well as enhancing physical & athletic performance and endurance at the cellular level to improve cardiovascular functioning and heart health. Give your cells what they need to prevent heart disease and improve cardiovascular functioning & heart health condition.
COQ 10 Improved Cellular Function:
COQ 10 Improved Cellular Function:
FREE RADICAL NUETRALIZER
Ideal for ATHLETES, CANCER & AIDS PATIENTS
HIGH ABSORBANCE FORMULA
ENSURE YOUR HEALTH
CoQ10 is also known as ubiquinone, a lipoidal vitamin-like substance similar in structure to vitamin K. Isolated in its pure form in 1957, Scientist F.L. Crane and his research team first extracted Coenzyme C)IO from animal tissue. Their research concluded that CoQlO was able to add or remove oxygen from a biologically active molecule.
Standard therapy for the prevention and treatment of reactions for:
cardiovascular disease, congestive heart failure, thyrotoxic heart failure, symptomatic mitral valve prolapse in children, cardiomyopathy adriamycin- (doxorubicin hydrochloride) induced cardiotoxicity, immunodeficiency, gastric ulcers, accelerated weight loss in obesity, diabetes mellitus, periodontal disease, muscular dystrophy, enhanced physical/athletic performance and endurance.
RESEARCH & STUDIES:Since 1974, there have appeared over 250 commercial preparations of CoQ10 supplied by more than 80 pharmaceutical companies. It is reported that in Japan, alone nearly 6 million now use CoQ10 each year, primarily for mild congestive heart failure and other disorders. Since 1957, researchers have found CoQ10 to be an essential substance in cell respiration, electron transfer and the control of oxidation reactions.
In one clinical periodontal disease study, 18 patients with periodontal disease received either 50 mg/day of CoQ10 or a placebo. All 8 patients receiving CoQ10 had less swelling, bleeding, redness, pain, exudate, loss of teeth and gingival pocket depth.
DOSES & DIRECTIONS:Directions:
Take 1 capsules three times daily, or as directed by a Health Care Professional.
The usual dosage of CoQ10 is 30 mg/day, with the range being between 20 to 50 mg/day. Only in cases of serious cardiac disease, or pre-adriamycin therapy have dosages over 100 mg a day been suggested.
Keep tightly closed in a cool dry place.
INGREDIENTS:Excipients: Rice Powder
Contains no artificial preservatives, coloring, flavors, salt, soy, sugar, starch, wheat or yeast.
Each capsule contains: Co-Enzyme Q10.....30mgs.
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*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease
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