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Source: Reuters Health
Summary:
Folic acid is a naturally occurring synthetic compound of B-vitamin commonly found in green leafy vegetables and fortified flour.
Folic acid supplementation early during pregnancy is recommended to prevent neural tube disorders such as spina bifida, but a recent study shows that it can reduce the risk of isolated cleft lip by up to 40 percent.
Cleft lip occurs when the roof of the mouth and the upper lip do not join correctly, more common with boys and a higher incidence with Asians.
Comment: Those who did not supplement with folic acid, but ate a diet rich in fruits and vegetables without taking folic acid supplements cut the risk by only 25 percent. In the case of folic acid it appears that supplementation is recommended.
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